Review of published studies of orally administered asbestos.
نویسنده
چکیده
There has been great public concern about the adverse health effects resulting from the presence of asbestos fibers in municipal drinking water supplies. This article reviews and summarizes the experimental findings of 11 published papers that have evaluated the carcinogenic potential of asbestos following its ingestion. The long-term, high-level ingestion of various types of asbestos fibers in more than one animal species failed to produce any definite, reproducible, organ-specific carcinogenic effect.
منابع مشابه
Commentary: penetration of asbestos through the digestive wall in rats*
Distribution studies on asbestos fibers administered to rats were performed with the electron microscope and were supplemented with studies involving use of tritiated and neutron-activated asbestos. Chrysotile filbers were injected into the stomach of rats, and 2-4 days later various tissues were solubilized and their fiber content studied. Fibers were isolated from the blood, spleen, omentum, ...
متن کاملRelative source contributions of diet and air to ingested asbestos exposure.
Reliable assessments of the relative contributions of diet (food, beverages, and orally administered drugs) and air (inhaled fibers) to total ingested asbestos exposure are not feasible due to the paucity of quantitative data on the subject. Instead, scenarios for both modes of exposure were developed from the limited information available to give crude estimates of ingestion of asbestos from t...
متن کاملAssociation Between Laryngeal Cancer and Asbestos Exposure: A Systematic Review.
Importance It has been debated whether a link exists between laryngeal cancer and asbestos exposure. Prior systematic reviews have been conducted on this topic, but no updates have been performed on the most recent literature since 2000. Objective To provide an updated systematic review of the association between laryngeal cancer and asbestos exposure. Evidence Acquisition A search of elect...
متن کاملClinical Pharmacology of the Antimalarial Quinine in Children
Quinine is the best studied drug for treating severe malaria in very young children. Quinine may be administered in pregnancy and, at therapeutic doses, malformations have not been reported. Some strains of quinine from Southeast Asia and South America have become resistant. Quinine is the treatment of choice for the drug-resistant severe Plasmodium falciparum. The antimalarial mechanism of qui...
متن کاملفاژ درمانی در عفونت های ناشی از باکتری های گرم منفی
Background and purpose: Infections caused by multidrug-resistant gram-negative bacteria are rising. Phage therapy is an effective treatment in infections resistant to treatment and progress has been made with its use and development in recent years. Phage therapy in treatment of gram-negative bacterial infections is not well investigated in clinical trials. Therefore, the aim of this study was ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Environmental Health Perspectives
دوره 53 شماره
صفحات -
تاریخ انتشار 1983